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Mitran, Sorin

Sorin Mitran

Chapman Hall 451

Research Interests

Computational simulation of multiscale, multiphysics systems. Data-driven constitutive relations for hyperelastic materials. Nonlinear mode reduction. Information geometry for reduced stochastic models.


Professional background

Politehnica University Bucharest, MSAE, 1985, PhD AE, 1995

Fellowships: University of Tokyo (1993), Karlsruhe Institute of Technology (1998-9), University of Washington (1999-2002)

Positions: University of North Carolina, Assistant Professor (2002-8), Associate Professor (2008-13), Professor (2013-present)


Research Synopsis

Development of numerical simulation tools to predict large-scale collective response of systems that are only known through interaction of microscopic components. Examples include: plastic deformation of metals from knowledge of lattice defect dynamics, microtubule mechanics from coarse-grained molecular dynamics, brittle fracture from accumulation of microcrack damage, protein folding from atomic-level dynamics, propagation of waves in biological media characterized at the cellular level.

Mathematical techniques include adaptive computation, mesh, algorithm, model, machine learning applied to prediction of constitutive laws, use of information geometry to extract stochastic process characterizations from data, nonlinear mode reduction based upon deep neural nets.


Representative Publications

Data‐Driven Reduced‐Order Model of Microtubule Mechanics
Y. Feng, S. Mitran,
Cytoskeleton, 75, 2, 45-60, 2018

A Numerical Model of Cellular Blebbing: A Volume-Conserving, Fluid–Structure interaction Model of the Entire Cell
J. Young, S. Mitran,
Journal of Biomechanics, 43, 2, 210-220, 2010

Metachronal Wave formation in A Model of Pulmonary Cilia
S. Mitran,
Computers & Structures, 85,11-14, 763-774, 2007


Canzani Sloan Research Fellow

Canzani Sloan Research Fellow

Yaiza Canzani, an assistant professor of mathematics… Dr. Saenz in Endeavors

Dr. Saenz in Endeavors

This interview with Dr. Saenz was featured in the July 2021 issue of UNC's research magazine, Endeavors